Drug Name

Protonix (Pantoprazole)

Drug Uses

Protonix blocks the production of stomach acid. It is prescribed to heal a condition called erosive esophagitis (a severe inflammation of the passage to the stomach) brought on by a persistent backflow of stomach acid (gastroesophageal reflux disease). Later, it may be prescribed to maintain healing and prevent a relapse. It is also used in the treatment of conditions marked by constant overproduction of stomach acid, such as Zollinger-Ellison Syndrome.

How to use

Protonix may be taken with or without food. Do not chew, crush, or split the delayed-release tablets. If you are taking antacids you may continue to do so.

Drug Class and Mechanism

Protonix is a member of the "proton pump inhibitor" class of acid blockers, which includes AcipHex, Nexium, Prilosec, and Prevacid.
Protonix blocks the production of stomach acid. It is prescribed to heal a condition called erosive esophagitis (a severe inflammation of the passage to the stomach) brought on by a persistent backflow of stomach acid (gastroesophageal reflux disease). Later, it may be prescribed to maintain healing and prevent a relapse. It is also used in the treatment of conditions marked by constant overproduction of stomach acid, such as Zollinger-Ellison Syndrome.

Missed Dose

If you miss a dose take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take two doses at once.

Storage

Store Protonix at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Protonix out of the reach of children and away from pets.

Warnings/Precautions

If Protonix gives you an allergic reaction, you'll be unable to use it.
Protonix has been known to cause several extremely rare--but very serious--side effects, including severe allergic reaction, severe swelling of the face and throat, eye damage, dangerous skin reactions, and inflammation of the pancreas. Seek emergency care immediately if you begin to have difficulty breathing or swallowing, or begin to develop blisters, eruptions, or peeling skin.
If you have a liver condition, make sure the doctor is aware of it. A dosage adjustment may be needed for anyone with serious liver disease.
Protonix has not been tested for safety or effectiveness in children.
If Protonix is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Protonix with the following:

• Ampicillin (Omnipen)
• Iron
• Ketoconazole (Nizoral)
• Warfarin (Coumadin)

Possible Side Effects

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Protonix.
More common side effects may include:

• abdominal pain,
• burping,
• diarrhea,
• gas,
• headache,
• insomnia,
• nausea,
• rash,
• vomiting.

More Information

Protonix is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If you have any questions about Protonix, please talk with your doctor, pharmacist, or other health care provider.